RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-222
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; immunohistochemistry
Target
PPP2R2A
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-222 modulates liver fibrosis in a murine model of biliary atresia
Year
2014
Function
"The expression of mir-222, pcna and akt was highly expressed in the mouse model of biliary atresia (ba), and the expression of ppp2r2a was significantly inhibited. Mir-222 regulates the fibrosis process in ba model."